Clinical Specialty
Dr. Weinand specializes in the surgical treatment of epilepsy. Another area of interest is neurosurgical management of chronic pain disorders like low back pain, cervical and lumbar radicular (arm and leg) pain, and chronic regional pain syndrome (CRPS).

Board Certification
American Board of Neurological Surgery, 1994

Research
My research activity is primarily concerned with medically intractable epilepsy. I also have produced research in collaboration with other neuroscientists in the areas of clincal neurosurgery and blood-brain barrier pathophysiology. Epilepsy research continues in selection of candidates for vagal nerve stimulation and temporal lobectomy. Recent research has been extended into the area of patient selection for spinal cord stimulation for treatment of intractable pain. Based upon research interest in cerebral perfusion, my basic neuroscience activitiy has emplhasized study of the human cerebral microvasculature. I continue to explore the pathophysiology of temporal lobe epilepsy with emphasis on discovering new prognostic factors predictive of success in epilepsy surgery. I also continue to collaborate with basic neuroscientists exploring the human blood-brain barrier and endothelia to improve understanding of the central nervous system pathophysiology.

My most recent research activity also includes cortical stimulaiton for stroke recover and Parkinson's disease.

Selected Publications

• Melgar M, Weinand ME.  Thyrocervical trunk-external carotid bypass for positional cerebral ischemia from common carotid occlusion: Report of three cases.  Neurosurgical Focus:14 (3), Article # 7, March, 2003 (www.neurosurgery.org/focus/mar03/14-3-nsf-toc.html).

• Brown JA, Lutsep H, Cramer S, Weinand M.  Motor cortex stimulation for
  enhancement of recovery after stroke: case report.  Neurological Research 25: 815-818, 2003.

• Gonzalez-Portillo G, Rivero S, Ahern GL, Labiner DM, Weinand ME. Normalization of Periictal Bihemispheric Cerebral Perfusion in Temporal Lobe Epilepsy.  Pathophysiology 11: 31-34, 2004.

• Cramer SS, Benson RR, Himes DM, Burra VJ, Janowsky JS, Weinand ME, Brown JA, Lutsep HL. Use Of Functional MRI To Guide Decisions in a Clinical Stroke Trial.  Stroke, 36: e50-e52, 2005. http://stroke.ahajournals.org/cgi/reprint/01.STR.0000163109.67851.a0v1

• Fiala M, Eshleman A, Cashman J, Lin J, Lossinsky A, Suarez V, Yang W, Zhang J, Popik W, Singer E, Chiappelli F, Carro E, Weinand ME, Witte M, Arthos J.  Cocaine increases HIV-1 neuroinvasion through remodeling brain microvascular endothelial cells.  Journal of Neurovirology, 11: 281-291, 2005.

• Melgar MA, Sahni D, Weinand ME.  Thyrocervical trunk-external carotid artery bypass for positional cerebral ischemia due to common carotid occlusion: Technical note.  Journal of Neurosurgery, 103: 170-175, 2005.

• Valdivia JMV, Dellon AL, Weinand ME, Maloney CT Jr..  Surgical treatment of peripheral neuropathy: Outcomes from 100 consecutive decompressions. J Amer Pod Med Assoc 95: 451-454, 2005.

• Melgar M, Mariwalla N; Madhusudan H, Weinand M.  Carotid endarterectomy without shunt: the role of cerebral metabolic protection.  Neurological Research 27: 850-856, 2005.

• Brown JA, Lutsep HL, Weinand M, Cramer SC.  Motor cortex stimulation for the enhancement of recovery from stroke: A prospective, multicenter safety study.  Neurosurgery 58: 464-473, 2006.

• Weinand M, Labiner D, Ahern G.  Correlation of electrocorticographic to clinical seizure onset and interhemispheric propagation times in temporal lobe epilepsy.  Pathophysiology 13: 233-236, 2006.
  http://dx.doi.org/10.1016/j.pathophys.2006.08.002

• Weinand ME, Farley C, Labiner D and Ahern G.  Time from ictal subdural EEG seizure onset to clinical seizure onset: An electrocorticographic time factor associated with temporal lobe epileptogenicity   Neurological research 2007 (in press).

• Cramer S, Parrish T, Levy R, Stebbins G, Ruland S, Lowry D, Trouard T, Squire S, Weinand ME, Savage C, Wilkinson S, Juranek J, Leu S, Himes DM. An assessment of brain function predicts functional gains in a stroke trial.  Stroke 2007 (in press).